Target. The study of the features of biochemical and morphometric indicators in patients with diabetes (diabetes) of type 2 and cognitive disorders (KN).
Material and methods. The main group was 72 patients suffering from type 2 diabetes, 20 people were included in the control group without cognitive violations from type 2 diabetes. Used: Montreal cognitive scale, level 1.5-anglyucitol, continuous monitoring of glucose levels, magnetic resonance imaging of the brain.
Results. As a result of data processing, it was revealed that in patients with type 2 diabetes and KN, a high level of glycated hemoglobin was recorded, however, there was no statistically significant difference in the level of 1.5 anhydroglucitol between the presented groups. Patients with KN have registered a decrease in the surface area of gray and white matter, as well as subcortical structures - hippocampus, a adjacent nucleus and shells on both sides, amygdaly and a pale ball on the right. The severity of KN correlated with the degree of polyneuropathy. In patients with a proliferative stage of retinopathy, a decrease in the volume of the tail nucleus, pale ball, shells and adjacent core is a decrease.
Conclusion. As a result of the study, it was revealed that patients with type 2 diabetes have the worst parameters of carbohydrate metabolism; They also found a decrease in cortical and subcortical structures of the brain. Key words: diabetes, cognitive disorders, variability, morphometry.