Home \ Neurology \ Arterial Hypertension and Cognitive Impairment: A Neurologist's Perspective

Arterial hypertension and cognitive disorders. The gaze of a neurologist

Author:
A.I. FEDIN

FGAOU in Russian National Research Medical University named after N.I. Pirogov »Ministry of Health of Russia, Moscow, Russia

Place of publication:
S.S. KORSAKOV JOURNAL OF NEUROLOGY AND PSYCHIATRY, 2023, Vol. 123, No. 11

Abstract: This article
presents a literature review on the relationship between cognitive impairment (CI) and arterial hypertension (AH). The pathogenetic mechanisms of AH are associated with the development of cerebral microangiopathy. Antihypertensive therapy (AHT) should take into account impaired cerebral blood flow autoregulation in cerebrovascular disease and critical stenosis of large cerebral arteries, especially in patients over 80 years of age. The importance of AHT, focused on cerebral perfusion pressure, the severity of AHT, and the patient's physical functioning, is emphasized. Neurocytoprotective therapy is recommended for the correction of AHT.

Key words: arterial hypertension, cognitive impairment, antihypertensive therapy, cerebral perfusion pressure.

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Actual

Results of an international multicenter, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of sequential therapy with ethylmethylhydroxypyridine succinate in patients in the acute and early recovery periods of ischemic stroke (IS)
Results of an international multicenter, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of sequential therapy with ethylmethylhydroxypyridine succinate in patients in the acute and early recovery periods of ischemic stroke (IS)
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Resolution of the Council of Experts "The possibilities of neuroprotective therapy in patients with arterial hypertension and cognitive disorders"
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The results of an international multicenter randomized double-blind-controlled study of evaluating the effectiveness of the effectiveness and safety of consistent therapy of patients with chronic brain ischemia with Mexidol and Mexidol Forte 250 (study of Memo)
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