Resolution of the Council of Experts "The possibilities of neuroprotective therapy in patients with arterial hypertension and cognitive disorders"

Presidium of the Council of Experts:

Martynov A.I., Doctor of Medical Sciences, Professor, Academician of the Russian Academy of Sciences, Professor of the Department of Hospital Therapy No. 1 of the A.I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation, President of the Russian Scientific Medical Society of Therapists (RSMST), Moscow

Tanashyan M.M., Doctor of Medical Sciences, Professor, Corresponding Member of the Russian Academy of Sciences, Deputy Director for Research, Federal State Budgetary Scientific Institution "Scientific Center of Neurology", Moscow

Malyavin A.G., Doctor of Medical Sciences, Professor of the Department of Phthisiology and Pulmonology of the Faculty of Medicine of the Federal State Budgetary Educational Institution of Higher Education “Moscow State University of Medicine and Dentistry named after A.I. Evdokimov” of the Ministry of Health of the Russian Federation, Chief Pulmonologist of the Ministry of Health of the Russian Federation for the Central Federal District, Secretary General of the Russian Scientific and Practical Society of the Russian Federation, Moscow

Participants in the Council of Experts:

Bogolepova A.N., Doctor of Medical Sciences, Head of the Department of Cognitive Impairments, Federal Center for Brain and Neurotechnology, Federal Medical and Biological Agency of Russia; Professor, Department of Neurology, Neurosurgery, and Medical Genetics, Faculty of Medicine, N.I. Pirogov Russian National Research Medical University, Moscow

Borovkova N.Yu., Doctor of Medical Sciences, First Deputy Director of the Institute of Therapy, Professor of the Department of Hospital Therapy and General Medical Practice, Federal State Budgetary Educational Institution of Higher Education “Volga Region Research Medical University” of the Ministry of Health of the Russian Federation, Nizhny Novgorod

Eliseeva L.N., Doctor of Medical Sciences, Professor, Head of the Department of Faculty Therapy, Federal State Budgetary Educational Institution of Higher Education “Kuban State Medical University” of the Ministry of Health of the Russian Federation, Chairman of the Krasnodar Regional Branch of the Russian National Medical and Orthopaedic Society, Krasnodar

Zhuravleva M.V., Doctor of Medical Sciences, Professor, Professor of the Department of Clinical Pharmacology and Propaedeutics of Internal Diseases of the Federal State Autonomous Educational Institution of Higher Education “First Moscow State Medical University named after I.M. Sechenov” of the Ministry of Health of the Russian Federation (Sechenov University), Chief Specialist – Clinical Pharmacologist of the Moscow City Department of Health, Moscow

Zakharov V.V., Doctor of Medical Sciences, Professor of the Department of Nervous System Diseases and Neurosurgery, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow

Koryagina N.A., Doctor of Medical Sciences, Professor of the Department of Outpatient Therapy, Perm State Medical University named after Academician E.A. Wagner, Ministry of Health of the Russian Federation, Vice President of the Association of Therapeutic Physicians of Perm Krai, Chairman of the Perm Regional Branch of the Russian Society of Therapists of the Ministry of Health of Perm Krai, Chief Therapist of the Ministry of Health of Perm Krai, Perm

Mikhin V.P., Doctor of Medical Sciences, Professor, Head of the Department of Internal Medicine No. 2, Federal State Budgetary Educational Institution of Higher Education “Kursk State Medical University” of the Ministry of Health of the Russian Federation, Kursk

Osipova I.V., Doctor of Medical Sciences, Professor, Head of the Department of Faculty Therapy and Occupational Diseases, Altai State Medical University of the Ministry of Health of the Russian Federation, Barnaul

Ostroumova O.D., Doctor of Medical Sciences, Professor, Head of the Department of Therapy and Polymorbid Pathology, Federal State Budgetary Educational Institution of Higher Professional Education “Russian Medical Academy of Continuous Professional Education” of the Ministry of Health of the Russian Federation, Moscow

Pozdnyak A.O., Doctor of Medical Sciences, Professor, Head of the Department of Therapy, Geriatrics and General Medical Practice, Kazan State Medical Academy – branch of the Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation, Kazan

Portnyagina U.S., Candidate of Medical Sciences, Associate Professor of the Department of Internal Medicine and General Practice (Family Medicine) of the Federal State Autonomous Educational Institution of Higher Education "North-Eastern Federal University named after. M.K. Ammosov", chief freelance specialist in therapy and general medical practice of the Ministry of Health of the Republic of Sakha (Yakutia), Yakutsk

Statsenko M.E., Doctor of Medical Sciences, Professor, Head of the Department of Internal Medicine, Volgograd State Medical University of the Ministry of Health of the Russian Federation, Volgograd

Tyrenko V.V., Doctor of Medical Sciences, Professor, Head of the Department and Clinic of Faculty Therapy, Federal State Budgetary Educational Institution of Higher Professional Education "S.M. Kirov Military Medical Academy" of the Ministry of Defense of the Russian Federation, Chief Cardiologist of the Ministry of Defense of the Russian Federation, St. Petersburg

Chesnikova A.I., Doctor of Medical Sciences, Professor, Head of the Department of Internal Medicine No. 1 of the Federal State Budgetary Educational Institution of Higher Education “Rostov State Medical University” of the Ministry of Health of the Russian Federation, Chief Therapy Specialist of the Southern Federal District, Rostov-on-Don

Place of publication:
THERAPY No. 10 (72) 2023

Resume by resolution:

• In hypertension, the brain is one of the target organs, the first symptoms of damage of which are vascular cognitive impairment (VCI).
• Neuropsychological testing is necessary to identify and assess the severity of VCI. Patients with hypertension are managed and assessed by a primary care physician.
• For effective treatment of SKN, antihypertensional therapy is not enough, a neuroprotection program is needed.
• The choice of a neuroprotector should be based on evidence and good tolerability. To reduce polypharmacy, it is necessary to focus on drugs with a multimodal mechanism of action (Mexidol®⁾.
• The recommended scheme of sequential therapy with Mexidol, according to the results of clinical studies, including randomized, 200-500 mg/day intravenously or intramuscularly for 14 days with a transition to a periral form, 250 mg 3 times/day for 60 days.
• Neuroprotection should be an integral part of the management of patients with hypertension. It is recommended to supplement the drug treatment algorithm for patients with hypertension by including ethylmethylhydroxypyridine succinate (Mexidol®⁾in the clinical guidelines for "Arterial Hypertension in Adults" (I10/I11/I12/I13/I15, according to ICD-10).