The effectiveness of combined therapy with Mexidol and cerebrolysine of chronic brain ischemia

Authors:
S.V. Berezhnaya ¹ , E.Z. Yakupov ² , Yu.A. Zakharov ³

¹ GAUZ "City Polyclinic No. 6" Kazan;
² GBOU VPO “Kazan State Medical University” of the Ministry of Health of the Russian Federation, Kazan;
³ GBOU VPO “Institute of Physics of Kazan (Volga) Federal University”, Kazan, Russia

Place of publication:
Journal of Neurology and Psychiatry, 5, 2016

Summary:
Purpose of the study. The study of the influence of the combination of Mexidol and Cerebrolysin as part of complex therapy on the state of the clinical status of patients with chronic brain ischemia (chemical) stage II on an outpatient basis. Material and methods. The study includes 36 patients with a diagnosis of stages II. Against the background of basic therapy, patients received 2 courses of combined therapy with Mexidol and Cerebrolysin for 6 weeks with an interval between courses of 3 months. After each course, the dynamics of patient complaints and objective clinical manifestations were evaluated. After the end of the treatment, the content of 13 chemical elements in the hair is determined by the atomic-emission method. Results and conclusion. Based on the clinical and neurological examination, the therapeutic effectiveness of the appointment of Mexidol and Cerebrolysine as a long neuroprotement in patients with the II stage, which was manifested by a reliable decrease in the severity of all the main symptoms under the influence of the therapy, is shown.