Optimization of lipidsiting therapy in patients with ischemic stroke and type 2 diabetes mellitus

Author:
L.A. Shchepanevich, Yu.A. Nikolaev, N.A. Dolgova

FGBNU "Research Institute of Experimental and Clinical Medicine", Novosibirsk

Place of publication:
Journal of Neurology and Psychiatry, 2, 2016

Summary:
The purpose of the study is to determine the effectiveness of Mexidol therapy to optimize the secondary prevention of vascular events through exposure to the indicators of vascular-trombocyte hemostasis and lipid blood spectrum in patients who have suffered ischemic stroke (AI), against the background of type 2 diabetes (SD2). Material and methods. Conducted a study of the content of general cholesterol, low -density lipoproteins, high density lipoproteins, blood -triglycerides in blood serum; The concentrations of the 4-plastic factor (4PF), β-tromboglobulin (βTH) and the villebrand factor in 68 patients with AI and SD2 were determined. Dynamic control of the studied indicators was carried out (1st, 21st day, 3rd and 6th months from the beginning of AI) amid therapy with Mexidol. Results and conclusion. Prolonged Mexidol therapy provides additional opportunities for normalizing the lipid blood spectrum and optimize secondary prevention of vascular events in patients with AI and SD2.

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