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Arterial hypertension and cognitive disorders. The gaze of a neurologist

Author:
A.I. Fedin

FGAOU in Russian National Research Medical University named after N.I. Pirogov »Ministry of Health of Russia, Moscow, Russia

Place of publication:
a journal of neurology and psychiatry named after S.S. Korsakova, 2023, T. 123, No. 11

Summary:
a review of the literature on the relationship of cognitive disorders (KN) with arterial hypertension (AH) is presented. The pathogenetic mechanisms of AH are associated with the development of cerebral microangiopathy. In antihypertensive therapy (AGT), disorders of the autoregulation of cerebral blood flow should be taken into account with cerebrovascular disease and critical stenosis of large brain arteries, especially in patients over 80 years old. The importance of AGT, focused on the level of cerebral perfusion pressure, the severity of KN and the physical functioning of patients, is emphasized. Neurocytoprotective therapy is recommended for the correction of KN.

Key words: arterial hypertension, cognitive disorders, antihypertensive therapy, cerebral perfusion pressure.

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