Epica. Study of the effectiveness and safety of Mexidol in the treatment of strokes

Time codes:
  • 00:00

    Mexidol® - evidence -based medicine

  • 03:06

    The purpose of the study of Epica.

  • 03:20

    Criteria for inclusion and research methods.

  • 05:52

    Assessment of neurological status and effects of the drug.

  • 07:00

    Comparability of groups and analysis features.

  • 07:50

    The primary criterion for evaluating effectiveness on the Rankin scale.

  • 10:20

    Secondary effectiveness criteria.

  • 10:28

    Assessment of the quality of life and the dynamics of changes.

  • 12:36

    Reducing the severity of symptoms of depression and cognitive disorders.

  • 13:38

    Patient profile and improvement of the quality of life.

  • 14:22

    Mexidol® after a stroke - treatment results 

Stakhovskaya Lyudmila Vitalievna - MD, professor, director of the Research Institute of Cerebrovascular pathology and stroke, department of fundamental and clinical neurology and neurosurgery of the IMF RNIMU named after N.I. Pirogov

Announcement:

Mexidol ® is a well -known drug with proven effectiveness, which with prolonged therapy helps patients return to active life. In the study of the drug Mexidol® Epica, a clinical assessment of the effectiveness and safety of the drug in patients with ischemic stroke was carried out.

Time codes:
  • 00:00

    Mexidol® - evidence -based medicine

  • 03:06

    The purpose of the study of Epica.

  • 03:20

    Criteria for inclusion and research methods.

  • 05:52

    Assessment of neurological status and effects of the drug.

  • 07:00

    Comparability of groups and analysis features.

  • 07:50

    The primary criterion for evaluating effectiveness on the Rankin scale.

  • 10:20

    Secondary effectiveness criteria.

  • 10:28

    Assessment of the quality of life and the dynamics of changes.

  • 12:36

    Reducing the severity of symptoms of depression and cognitive disorders.

  • 13:38

    Patient profile and improvement of the quality of life.

  • 14:22

    Mexidol® after a stroke - treatment results 

Block of articles on this topic

The results of a randomized double blind multicenter placebo-controlled in parallel groups of the study and safety of Mexidol with prolonged consistent therapy in patients in acute and early restorations. Periods

Authors:
L.V. Stakhovskaya 1 , N.A. Shamalov 1 , DR Khasanova 2 , E.V. Melnikova 3 , A.S. Agafin 4 , K.V. Golikov 5 , E.I. Bogdanov 6 , A.A. Yakupova 6 , L.V. Roshkovskaya 7 , L.V. Lukin 8 , T.M. Lokstanova 9 , I.E. Patrunenova 10 , L.A. Shchepankevich 1 1

1 Research Institute of Cerebrovascular Pathology and Stroke of the Federal State Budgetary Institution “Russian National Research Medical University named after N.I. Pirogov »Ministry of Health of Russia, Moscow, Russia;
2 GAUZ "Interregional Clinical and Diagnostic Center", Kazan, Russia;
3 St. Petersburg GBUZ "City Hospital No. 26", St. Petersburg, Russia;
4 St. Petersburg GBUZ "City Hospital No. 40 of the Resort Administrative District", St. Petersburg, Russia;
5 St. Petersburg GBUZ "City multidisciplinary hospital No. 2", St. Petersburg, Russia;
6 FSBEI in Kazan State Medical University of the Ministry of Health of Russia, Kazan, Russia;
7 St. Petersburg GBUZ "Nikolaev Hospital", St. Petersburg, Russia;
8 GBUZ "Vsevolozhsk Clinical Interdistrict Hospital", Leningrad Region, Russia;
9 Mubz "City Clinical Hospital No. 1 named after N.I. Pirogov ", Samara, Russia;
10 GBUZ "Samara Regional Clinical Hospital named after V.D. Seredavina ”, Samara, Russia;
11 FGBNU "Scientific Institute of Experimental and Clinical Medicine", Novosibirsk, Russia.

The effectiveness and safety of Mexidol in patients of different age groups in the acute and early recovery periods of the hemispherical ischemic stroke (the results of subanalysis of a randomized double blind multicenter placebo-controlled epic study)
Review of clinical recommendations for the treatment and prevention of ischemic stroke

Author:
A.I. Fedin, K.R. Badalyan

FSBEI in Russian National Research Medical University named after N.I. Pirogov »Ministry of Health of Russia, Moscow, Russia

The effect of therapy with the drug Mexol on the regression of neurological deficiency and a functional outcome in patients with ischemic stroke: a systematic review and meta analysis

Authors:
I.A. Voznyuk 1.2 , S.V. Kolomensev 2.3 , E.M. Morozova 1

Results of a Randomized, Double-Blind, Multicenter, Placebo-Controlled, Parallel-Group Study of the Effi Cace and Safety of Mexidol in Prolonged Sequential Therapy of Patient S in the Acute and Early Recovery Stages of Hemisphereic Stroke (The Epica Study)

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