Cognitive disorders in patients with arterial elderly and senile hypertension

Author:

Sharashkina N.V., Ostapenko V.S., Tkacheva O.N., Runikhina N.K., Kotovskaya Yu.V., Mkhitaryan E.A., Lysenkov S.N.

Place of publication:

Cardiovascular therapy and prevention, 2017; 16 (3)

Target. To study the cognitive status in elderly patients with arterial hypertension observed in clinical conditions.

Material and methods. The study included 356 patients; The average age is 74.9 ± 6.1 years, 80.4% of them are women. To evaluate cognitive functions before and after treatment, neuropsychological testing using MMSE - a brief scale for assessing mental status was performed; watch drawing test; The test of literal and categorical associations.

Results. In the group of patients <80 years, the severity of cognitive disorders by MMSE correlated with blood pressure (blood pressure): for systolic blood pressure (r = -0.22, p = 0.0003), for diastolic blood pressure (R = -0,13, p = 0.03), i.e. In patients with higher blood pressure, low points were noted on the scale of assessing the cognitive status based on the results of the correlation analysis of Spearman. While in group ≥80, both correlations were insignificant, for systolic blood pressure (r = -0.05, p = 0.64), for diastolic blood pressure (r = -0.13, p = 0.25).

Conclusion. Patients of elderly and senile ages with arterial hypertension should have a differentiated approach to the level of blood pressure depending on age and the presence of cognitive disorders, an integrated approach to therapy in these patients can prevent further progression of cognitive status worsening.

Key words: arterial hypertension, cognitive impairment, dementia, elderly.