Features of the manifestation of anxiety in patients of older age groups with different types of moderate cognitive disorder

Author:

A.P. Sidenkova

FSBEI in "Ural State Medical University" of the Ministry of Health of Russia, Yekaterinburg, Russia

The purpose of the study.

Studying the structure of an alarming symptom complex in patients of late age with amnestic, disregional and polymodal types of moderate cognitive disorder (UKR) and determining the clinical efficiency of ethylmethylhydroxypyridine (Mexol).

Material and methods.

The selective study included 32 patients with both sexes over 55 years old from UKR (F06.7 according to ICD-10), who applied for medical help for anxiety. The inclusion criteria were compensation for concomitant somatic pathology, the lack of
significant stress events during the year, the lack of depression. They used clinical-psychopathological and psychometric methods: Hamilton's scale for evaluating anxiety (HAM-A), a geriatric depression questionnaire (GDS), a brief scale for evaluating mental status (MMSE), a scale of a general clinical impression (CGI-S, CGI-I), a scale for evaluating stress events. The main criterion for the effectiveness of 4-week therapy with Mexidol (375 mg per day) was the reduction of a common score on the scale of us-a. Results and conclusion. At the time of inclusion in the study,
the average points on the HAM-A and MMSE scales amounted to 39.9 ± 3.18 and 25.7 ± 0.6, respectively. When studying the structure of an alarming state in people with amnestic, dysregulatory and polymodal types of UKR, it was found that the phenomenology of an alarming symptom complex with these types of UKR is different. A re-assessment of anxiety on the HAM-A scale was carried out after 1, 2 and 4 weeks of therapy with Mexidol. Improving the mental state was noted with all types of UKR, but the proportion of people with a significant improvement was higher with amnestic and dysregulatory types compared
to polymodal. The development rate of the anti -aircraft effect was noted more with the dysregulatory type of UKR. In all patients, the use of Mexidol contributed to an increase in the stability of the function of attention and correction of autonomic dysfunction.

Key words: anxiety, moderate cognitive disorder (UKR), neuropsychological types of UKR, Mexidol.