Chronic cerebrovascular failure: description of the clinical case

Authors:

Vakhnina N.V. , Gromova D.O. , Zakharov V.V. , Tarapovskaya A.V.

Place of publication:

Therapeutic archive 4, 2016

Chronic cerebrovascular insufficiency (CCI) results from cerebral microangiopathy, most often due to uncontrolled hypertension. The brain suffers from repeated "silent" infarctions and/or microbleeds without clinical manifestations of stroke or chronic cerebral ischemia. The main manifestation of chronic, progressive, non-stroke vascular brain damage is progressive cognitive impairment, characterized by a predominance of attention deficit, a decrease in cognitive performance, and impaired planning and control, with relative preservation of memory.
These impairments are typically accompanied by emotional changes, such as affective instability and depression. A typical clinical case of CCI is described, the mechanisms underlying neurological symptoms are explored, and current approaches to managing these patients are outlined.

Key words: chronic cerebral ischemia, cerebrovascular insufficiency, vascular cognitive impairment.