Authors:
O.D. OSTROUMOVA1,2, M.S. CHERNYAEVA3
1Federal State Budgetary Educational Institution of Higher Education, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Healthcare of the Russian Federation, Moscow, Russia;
2Federal State Autonomous Educational Institution of Higher Education, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Healthcare of the Russian Federation, Moscow, Russia;
3Federal State Budgetary Educational Institution of Higher Professional Education, Central State Medical Academy, Administrative Department of the President of the Russian Federation, Moscow, Russia
Place of publication:
JOURNAL OF NEUROLOGY AND PSYCHIATRY, 9, 2018
Abstract:
This article presents a review of Russian and international literature devoted to the impact of arterial hypertension (HTN) on the risk of cognitive impairment. Data from large studies demonstrating the relationship between blood pressure and the risk of vascular dementia and Alzheimer's disease in the elderly and very old, as well as the role of antihypertensive therapy, are considered. Evidence is presented of the negative impact of hypertension in middle age on cognitive function in the elderly. The importance of an interdisciplinary approach to the treatment of cognitive impairment by cardiologists and/or therapists in collaboration with neurologists, as well as comprehensive treatment regimens including risk factor correction and neuroprotective therapy, is emphasized. Key words: arterial hypertension, cognitive impairment, vascular dementia, Alzheimer's disease, antihypertensive therapy.